Vitamin D Synthesis: Acute Effect of Sun Exposure

Vitamin D Synthesis: Acute Effect of Sun Exposure


We know by now that we need to eat the right foods, need to work out, and do stuff that is healthy for us. Because maintaining good health does not happen by accident, it requires work and smart lifestyle choices. But sometimes when we wake up at 6 am to hit the gym before work or shunning the donuts in breakfast, it’s easy to lose sight of for what are we doing all these. So here are some top articles choices that can keep you motivated to lead a healthy lifestyle and keep diseases at bay.

Vitamin D Synthesis: Acute Effect of Sun Exposure

The effects of acute exposure to sun are sunburn and synthesis of vitamin D. vitamin D is one of the vitamin (other vitamin which is synthesized in the body is vitamin K in the gut, by gut flora but not adequate for human requirement) which human body can synthesize in the body in adequate amount and vitamin D is required by human body for good health state. Vitamin-health is an important aspect for good health state and vitamin D is vital for this.

How vitamin D is synthesized in the skin?

Upon exposure of skin to sunlight (UV-B or ultraviolet B, which consists of wavelengths between 290 and 320 nm), there occurs photolysis of epidermal 7-dehydrocholesterol converting it to pre-vitamin D3. This pre-vitamin D3 than then undergoes isomerization which is temperature-dependent to form the stable hormone vitamin D3. This stable hormone vitamin D3 then diffuses to the blood vessels of the dermis (the inner layer of skin) and circulates systemically where it is converted to the functional hormone 1,25-dihydroxyvitamin D3 or 1,25(OH)2D3 (this active form is used by human body for good vitamin-health). Vitamin D metabolites from the circulation or those produced in the skin itself can augment epidermal differentiation signaling.

There is controversy regarding the importance of sun exposure in vitamin D synthesis. Bu at present, what is more important is, to emphasize that the use of sunscreens does not substantially diminish vitamin D levels. Aging can substantially decreases the ability of human skin to produce vitamin D3 photo catalytically, the widespread use of sunscreens that filter out UV-B has led to concern that vitamin D deficiency may become a significant clinical problem in the elderly. But vitamin D is also available in many food sources and elderly people might suffer from vitamin D deficiency due to use of sunscreen that filter UV-B rays is unfounded.

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