Osteoporosis Fracture Treatment & Estrogen

Osteoporosis Fracture Treatment & Estrogen


We know by now that we need to eat the right foods, need to work out, and do stuff that is healthy for us. Because maintaining good health does not happen by accident, it requires work and smart lifestyle choices. But sometimes when we wake up at 6 am to hit the gym before work or shunning the donuts in breakfast, it’s easy to lose sight of for what are we doing all these. So here are some top articles choices that can keep you motivated to lead a healthy lifestyle and keep diseases at bay.

Osteoporosis Fracture Treatment & Estrogen

Several epidemiological study suggests that estrogen replacement in women (post menopausal women) can reduce osteoporotic fractures by 50% (average of all fractures associated with osteoporosis), including the most common fracture associated with osteoporosis, i.e. hip fracture. The benefits of estrogen in reducing hip and other osteoporotic fractures are maximum if estrogen replacement is started as early as required and continued. The beneficial effects (residual benefits) of estrogen replacement disappear if it is discontinued for more than 10 years.

The Women’s Health Initiative (WHI) study data (which involved more than 16,000 postmenopausal healthy women) shows that hormone therapy (estrogen) reduces the risk of hip and clinical spine fracture by 34% as well as all other clinical fractures by at least 24%. Many other studies (although these are smaller than Women’s Health Initiative study) also showed that hormone therapy can definitely reduce risk of fracture associated with osteoporosis. The large studies such as Women’s Health Initiative also shed light to many other unanswered medical conditions.

If progestin is combined with estrogen, for management of osteoporosis and for reduction of osteoporotic fractures, other health problems such as breast cancer incidence, stroke and heart attacks may increase. That is the reason reduction of osteoporotic fractures should be done with estrogen alone, without adding progestin. Addition of progestin can cause increase in breast cancer risk, venous thromboembolic events, heart attacks etc. The Women’s Health Initiative (WHI) study has shown that only estrogen should be used for management (reduction of risk of fracture) osteoporosis.

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1 Comment

  • Osteoporosis Is A Threat To Men, Too
    November 29, 2010 - 1:30 pm

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