Diagnosis of Type 1 Diabetes Mellitus

Diagnosis of Type 1 Diabetes Mellitus

We know by now that we need to eat the right foods, need to work out, and do stuff that is healthy for us. Because maintaining good health does not happen by accident, it requires work and smart lifestyle choices. But sometimes when we wake up at 6 am to hit the gym before work or shunning the donuts in breakfast, it’s easy to lose sight of for what are we doing all these. So here are some top articles choices that can keep you motivated to lead a healthy lifestyle and keep diseases at bay.

Diagnosis of Type 1 Diabetes Mellitus

The diagnosis of diabetes mellitus (type-1 diabetes as well as type-2 diabetes and other forms of diabetes such as Gestational diabetes, other specific types of diabetes) is based on clinical features of diabetes and laboratory findings. All forms (types) of diabetes are characterized by persistent or recurrent hyperglycemia (high blood sugar levels) and symptoms such as, frequent urination, excessive thirst (may be as a result of frequent urination and passing of large volume of urine in a unit time), excessive hunger (despite excessive hunger diabetes patients are usually underweight/thin and not obese, especially if diabetes is present for long duration) and other associated symptoms (especially if any complication develop due to presence of diabetes in a patient for long duration, such as eye problems, kidney problems etc.) etc.

Diagnosis of diabetes is established (according to World Health Organization criteria for diagnosis of diabetes) if any of the following criteria is fulfilled:

  • Fasting plasma glucose of 126 mgs/100 ml (7.0 mmol/liter) or higher.
  • Plasma glucose of 200 mgs/100 ml (11.1 mmol/liter) or higher, two hours after a 75 gram oral glucose load.
  • Symptoms of hyperglycemia and a random plasma glucose of200 mgs/100 ml (11.1 mmol/liter) or higher.

ADA (American Diabetes Association) recommends another criterion for diagnosis of diabetes, i.e. glycosylated (glycated) hemoglobin or hemoglobin A1C of 6.5 or higher, but WHO is yet to adopt this criterion for diagnosis of diabetes.

After diabetes is diagnosed it may be required to find the type of diabetes, i.e. type-1 diabetes or type-2 diabetes. Type-1 diabetes usually occurs at an early age, in first or second decade of life. Type-1 diabetes is an autoimmune disease and demonstration of auto antibodies can differentiate type-1 diabetes from type-2 diabetes. it is also possible to predict appearance of type-1 diabetes before diabetes/hyperglycemia sets in, by demonstrating the diabetes related auto antibodies such as insulin auto antibodies, islet cell auto antibodies, auto antibodies against 65kDa etc. Appearance of diabetes before second decade of life strongly suggests type-1 diabetes.

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  • Avatar for Winter
    Winter July 02, 2011 08.51 am

    Now I know who the brainy one is, I?ll keep lokonig for your posts.

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