Treatment of Gastritis

Treatment of gastritis depends on the cause of gastritis. For example if gastritis is due to intake of NSAIDs for long duration, the offending medication (in this case NSAIDs) should be withdrawn, if gastritis is due to infection by H. pylori, treatment should be directed towards eradication of H. pylori. If gastritis is due to chronic alcohol consumption, it should be stopped or reduced as part of treatment. Treatment of gastritis also includes measures to reduce acid production in stomach or neutralization of acid in stomach by use of antacids, because in most of the cases it is the stomach acid that leads to signs and symptoms of gastritis.

The treatment measures of gastritis include eradication of H. pylori; reduce production of stomach acid, neutralization of stomach acid etc. Your doctor will decide what type of treatment modality is required for you based on causes of gastritis and risk factors associated with you.

Eradication of H. pylori:

If urea breath test indicate presence of H. pylori, attempt should be made to eradicate them. There are different regimens available for eradication of H. pylori. Regimens include one week and two week duration.

One week regimens for eradication of H. pylori:

  1. Amoxicillin 500 mg three times a day (or clarithromycin 250 mg two times a day), plus metronidazole or tinidazole 500 mg three times a day, plus omeprazole 20 mg two times a day for one week.
  2. Amoxicillin 500 mg three times a day, plus clarithromycin 250 mg three times a day, plus omeprazole 20 mg two times a day for one week.

Two week regimen for eradication of H. pylori:

1.      Amoxicillin 750 mg two times a day, plus clarithromycin 500 mg two times a day, plus omeprazole 40 mg once a day for two weeks.

2.      Amoxicillin 750 mg three times a day, plus metronidazole 500 mg three times a day, plus ranitidine 300 mg once a day for two weeks.

Reduce production of stomach hydrochloric acid:

Medications that reduce acid production in the stomach are used as part of treatment of gastritis, because finally it is stomach acid that causes gastritis, whatever may be the aggravating/causative factor. Proton pump inhibitors such as omeprazole, lansoprazole, pantoprazole, rabeprazole etc. are used commonly for this purpose. H2 blockers such as ranitidine, famotidine etc. may also be used for the same purpose.

Neutralization of stomach acid:

Because stomach acid is the reason for gastritis, neutralization of stomach acid can reduce severity of signs and symptoms of gastritis. Antacids are suitable for this purpose. Antacids can provide immediate relief from symptoms of gastritis by rapidly neutralizing stomach acid.

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