Transmission and Prevention of Rotavirus Infection

How rotavirus infection is transmitted?

The route of transmission of rotavirus is feco-oral. Contact with contaminated hands, surfaces and objects can transmit the virus and initiate infection and diarrhea. Respiratory route is also considered to transmit the virus from one person to another. The number of rotavirus particle in infected person’s feces is estimated to be more than 10 trillions and the infective dose is only 10-100 virus particles. Presence of such huge numbers of virus and the small size of infective dose required makes it ideal for mass transmission of rotavirus. Another important aspect in high incidence and infectivity of rotavirus is the less effectiveness (may be ineffectiveness) of standard sanitary measures used for elimination of bacteria, virus and parasites. This can be easily understood by the fact that the incidence of rotavirus infection is similar in countries with high as well as low health standards, unless there is mass and routine vaccination program against rotavirus infection. The stability of rotavirus in normal environment also makes the transmission of the virus easy.

How to prevent rotavirus infection?

It is not possible to prevent transmission and infection of rotavirus by improving sanitation and drinking water quality (as standard sanitary measures used for elimination of bacteria, virus and parasites can not eliminate the rotavirus) by providing safe drinking water, the only effective way to prevent rotavirus infection and diarrhea is vaccination. The numbers of rotavirus diarrhea and hospitalization is high despite providing safe drinking water.

The rotavirus vaccine:

At present there are two safe and effective vaccines available against rotavirus A. One is marketed by GlaxoSmithKline with brand name “Rotarix” and the other marketed by Merck with brand name “RotaTeq”. Both vaccines are oral vaccines and approved by USFDA and licensed for use in more than 100 countries. But only few countries (including US) use it as routine vaccination. World Health Organization at present recommends use of rotavirus vaccine in routine national immunization programs, after clinical trial in 2009, which found the vaccine to be safe and effective.

The Rotavirus Vaccine Program aims at reducing infant and child morbidity and mortality in poor countries by making the rotavirus vaccine available in those countries.

Related Posts

8 Comments

  • Norwegian Translation March 26, 2011 10.31 pm

    Great article . Will definitely copy it to my blog.Thanks.

    Reply 
  • what happened to limewire April 13, 2011 12.59 pm

    Hi there, I found this blog once, then lost it. Took me forever to arrive back and discover it. I wanted to view what comments you got. Great blog by the way.

    Reply 
  • Beryl Reesor April 16, 2011 11.44 pm

    Extremely rated post. I be taught something totally new on different blogs everyday. Deciding on one . stimulating to read the paper content material from different writers and be taught a bit something from their website. I’d like to use certain of this content material on my blog you’re mind. Natually I’ll give a hyperlink here we’re at your internet-site. Respect your sharing.

    Reply 
  • Hotels in Salzburg April 19, 2011 10.08 am

    Really? It really is excellent to witness anyone finally begin addressing this stuff, however I’m still not really certain how much I agree with you on it all. I subscribed to your rss feed though and will certainly keep following your writing and possibly down the road I may chime in once again in much more detail. Cheers for blogging though!

    Reply 
  • download the last airbender movie April 19, 2011 11.07 am

    I observed your site through search engine several months ago, and luckily, this really is the only information I was looking for the last hours

    Reply 
  • watch free tv and movies online April 21, 2011 12.34 pm

    Its like you read my mind! You appear to know so much about this, like you wrote the book in it or something. I think that you could do with a few pics to drive the message home a bit, but other than that, this is magnificent blog. A fantastic read. I will definitely be back.

    Reply 
  • dari mana tv
    July 3, 2012 - 2:28 pm

  • click here September 27, 2012 12.16 am

    I like it whenever people come together and share thoughts, great blog, keep it up.

    Reply 

Leave a Comment

Loading...