Posts Tagged ‘dementia’

Truth About Alzheimer’s Disease

Alzheimer's disease (AD) is the most common cause of dementia in western countries. AD is caused to lack of acetylecholine in brain. Approximately 10% above 70 years have significant memory loss and at least more than half of this is due to Alzheimer's disease. AD most commonly presents as subtle loss of memory and it is followed by slowly progressive memory loss, and that has a course of several years (8-10 years). AD can occur at any time during adult life. Cost of treatment in USA is nearly $ 75,000 per year, which is a staggering sum of money, which also extracts a heavy emotional toll on family and friends and caregivers. Patho physiology of AD is diffuse atrophy of cerebral cortex and secondary enlargement of ventricular system. Neuritic plaques containing A? amyloids are seen in microscopy, and also accumulation of A? amyloids in the arterial walls of cerebral blood vessels. Four susceptible genes have been identified to cause AD.

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