2nd Cause of Acne (out of 4 main causes)
An important cause of acne is ductal hyper cornification that can be seen as microcomedones histologically. Clinically they can be seen as blackheads, whiteheads and macrocomedones. There is strong correlation between acne and number & size of microcomedones. Comedones are due to abnormal proliferation and differentiation of ductal keratinocytes . They are due to retention of hyper proliferating ductal keratinocytes . The hyper proliferation has been confirmed by an increase in H-thymidine labeling of comedones.
Categories: Acne Tags: Blackheads, isopropyl myristate, Linoleic acid, Macrocomedones, propylene glycol, Whiteheads
