Non-Modifiable Risk Factors of Osteoporosis

ID-100116449There are several risk factors of developing osteoporosis, some of the risk factors of osteoporosis are non-modifiable, and some risk factors are potentially modifiable. Osteoporosis is also known complication of various medical disorders. Various medications used for different medical conditions can lead to osteoporosis and use of medications can be considered potentially modifiable risk factor of osteoporosis. However, in many cases medications are unavoidable and osteoporosis has to be accepted side effect of those medications.

Non-modifiable risk factors of osteoporosis are:

  • Older age is the most common and one of the important non-modifiable risk factor of osteoporosis. We can not modify old age. At older age women are at higher risk in compare to men (although men are also at high risk of osteoporosis at old age), due to menopause and estrogen deficiency after menopause. In older men reduced level of testosterone is a risk, but less profound than estrogen deficiency in women.
  • Heredity and genetic factors are also important. Osteoporosis tend to be more common among family members with osteoporosis. Fracture is to certain extent heritable and individuals with family history of fracture are at higher risk of developing osteoporosis.
  • Physical built: individuals with small stature are at greater risk of developing osteoporosis, than well-built individuals.
  • Race: Asians and Europeans are at higher risk of osteoporosis in compare to other races
  • History of previous fracture: if an individual have history of one or more fractures, he/she is at higher risk of osteoporosis (twice the normal) in compare to other individuals of same age, sex, race etc. without any history of fracture.
  • Early menopause and hysterectomy (surgical removal of uterus) are risk factors of osteoporosis
  • Sex: females are at higher risk of osteoporosis in general in compare to men. Menopause and estrogen deficiency (due to any cause) are responsible for higher risk.

One can not modify the non-modifiable risk factors of osteoporosis. However preventive measures can be taken to reduce the risk of development of osteoporosis, such as hormone replacement therapy, use of medications such as bisphosphonates for high risk individuals.

“Image courtesy of¬†imagerymajestic / FreeDigitalPhotos.net”.

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